UroFuraginum x 30 tabl.
Composition
active substance: furagin (furazidin);
1 tablet contains furagin (furazidin) 50 mg;
excipients: potato starch, calcium stearate, twin-80, milk sugar.
Indications
Furagin for the treatment of acute and chronic pyelonephritis, cystitis, urethritis.
Contraindications
Individual hypersensitivity to Furagin (idiosyncrasy). The drug is contraindicated from the 38th to the 42nd week of pregnancy and during lactation. Children < 5 years of age (weighing less than 20 kg).
Caution should be exercised when prescribed to patients with impaired renal function, deficiency of phosphate dehydrogenase.
Dosage and administration
Furagin should be taken orally, after meals, with plenty of water, in a dose of 100 - 200 mg 2 - 3 times daily.
In children > 5 years of age (weighing > 20 kg) the drug should be prescribed in a daily dose of 5.7 mg/kg of the bodyweight. Depending on the severity and clinical course of the disease, treatment continues for 7-10 days. If no side effects have occurred, treatment can be repeated in 10 - 15 days, when necessary.
For prophylaxis, the medication should be prescribed in a dose of 50 mg (1 tablet) once daily (preferably overnight).
In case of overdose, acute toxic hepatitis, hematotoxicity (hemolytic or megaloblastic anemia, leukopenia), neurotoxicity (polyneuritis) may occur.
In this case the drug should be discontinued, the stomach should be washed out and medical attention should be sought.
Side effects
Possible are decreased appetite or loss of appetite, heartburn, nausea, occasional vomiting, stomach pain, dizziness, allergic reactions. Occasionally neurotoxic effects have been reported - headache, dizziness, insomnia, asthenia, excessive sweating. In these cases the dose should be reduced or even discontinued. The side effects are less severe when the drug is taken only after meals and with plenty of liquid.
Prolonged administration in high doses and prolonged administration in low doses to patients with impaired excretory renal function, cardiac decompensation, alcoholism may result in polyneuritis.
Acute hemolytic anemia may develop in cases of hepatic insufficiency, prolonged treatment or administration of high doses in patients with hereditary deficiency of pentosophosphate pathway erythrocyte enzymes.
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